What Can Paracetamol Overdose Do To You?

by Purva Mewar | Medicine | Friday, August 24th, 2007

Let’s get to the most important point first. If a paracetamol overdose is suspected, hospital treatment should be sought without delay. Ideally within 12 hours of having taken the overdose. Treatment must always be supervised in a hospital.

The recommended dose of paracetamol for a single adult is two standard 500 mg tablets. Researches have reported that the threshold for liver damage to start from a single paracetamol overdose is 15 gms (30 tablets).

An important point my however noted that as per the standard hospital guidelines, they allow an extra cover or safety margin and consider that liver damage could start to occur at a single overdose of 24 standard tablets or 150 mg/kg body weight, (whichever is the smaller). The overdose border or threshold may be lowered in a person on prescription medicines, or someone who is an alcoholic or is undernourished to some extent.

Symptoms: Overdose Of Paracetamol often shows no symptoms within the first 24 hours after the overdose. In some cases although there may be mild nausea and vomiting. If the overdose is large then liver function may start deteriorating leading to either of these; jaundice, confusion, and loss of consciousness. Death due to overdose of Paracetamol is rare but when it occurs it is in majority of cases due to liver failure.

In severe poisoning, hepatic failure may progress to encephalopathy, haemorrhage, hypoglycaemia, cerebral oedema, and like discussed earlier, death. Abnormalities of glucose metabolism and metabolic acidosis may occur. Acute renal failure with acute tubular necrosis, strongly suggested by loin pain, haematuria and proteinuria, may develop even in if there is no severe liver damage. Cardiac arrhythmias and pancreatitis have also been reported as a result of overdose of Paracetamol.

Treatment of a serious paracetamol overdose is done by administration of an antidote, which can defeat and combat the toxic effects of the overdose.

Immediate treatment is essential in case of paracetamol overdose. Wen a person has had an overdose of paracetamol, and there are no significant early symptoms, patients should still be referred to hospital urgently for immediate medical attention. Symptoms may be limited to nausea or vomiting and may not be severe but the risk of organ damage has already set in so steps should be takne immediately.

Docotors normally consider treating such patients with activated charcoal if the overdose has been taken within 1 hour. Likewise, treatment with N-acetylcysteine may be used up to 24 hours after ingestion of paracetamol. However one must know that the maximum protective effect is obtained up to 8 hours after ingestion. The effectiveness of the antidote diminishes sharply after this time. If vomiting is not a problem, oral methionine may be a suitable substitute for remote areas, outside the hospital.

For a common person with an overdose of paracetamol it is best to visit the doctor and seek immediate advice. If you are soemone you know has had an overdose of paracetamol then whether to not symptoms shtart to surface you should visit the doctor. Earlier the beter. Best within one hour of intake of it. And starts getting really dangerous after 24 hours of having takent he overdose. No self medication, no taking cues from people who have experienced this horror before or checking out the net for immediate assisttance. Keep it simple. VISIT THE DOCTOR.



 
79 Comments:
post a comment
Comment by t
2007-09-08 04:28:19

does anyone know if it can cause damage about 4-5 months after. Because i had the antidote in
about march but i’ve been having pains in my tummy and differnet sides (it changes!) every few weeks.

 
Comment by AIMEE
2008-04-07 10:27:02

i HAD ANTIDOTE 6 YRS AGO AFTER 120 PARA WEIGHING 5.5 STONE.
WEIGHT LOSS NOT SELF INFLICTED – AND OD A RESULT OF SUCH DRASTIC W.LOSS UNEXPLAINED
STRAIGHT AFTER OD, ADDICTED TO PAINKILLERS AND WEIGHT DRAMATICALLY INCREASED TO DOUBLE DESPITE NORMAL FOOD INTAKE NORMAL

ANY ANSWERS WHY PAINKILLERS OR OD OR ANTIDOTE COULD CAUSE DRASTIC WEIGHT GAIN?

 
Comment by Dan
2009-08-01 07:42:34

reply to ‘AIMEE’

a good friend of mine had the same problem with weight gain after od.

your liver is the main organ which controls your motabilism, and if it is damaged or you get liver failure your motabilism will dissapear, meaning you have no body organs that will help against weight gain. all fat will sit in your body and not be lost because your liver is damaged

 
Comment by nicol
2009-08-26 08:51:40

I took an overdose of paracetmol and I had the antidote 12 hours later and survived I stil look yellow
And I still have pains in my stomach and right side. People have told me that no amount of paracetmol
Can kill you is this true

Comment by Woo Woo
2010-06-02 21:36:28

you must have problems with your liver, it will catch up with you in the future or anytime. people need to learn that taking paracetamol is a one way ticket to death… or a life being disabled if you fail at dying.

 
 
Comment by mia
2010-02-07 23:45:08

I took an overdoes of paracetamol and since then I’ve been experiencing headaches, nausea and I’ve been fighting off from losing consciousness. I also have pains in my stomach and I couldn’t sleep properly at night because of it. Is it because of the overdose? Or is it something else?

Comment by casey
2010-03-01 15:56:27

reply to mia, last wednesday/thursday i took an overdose of paracetamol, got rushed into hospital and was kept in for a few days, it takes 150mg/1kg of your body weight to kill you, mine was 198mg/1kg, they discharged me on the saturday and recently i have been suffering from the exact same thing, if you find anything out please mail me.

 
 
Comment by Gem
2010-02-09 13:27:42

I know someone that died after a paracetemol overdose. He was in hospital for weeks. He started to look better and made plans for the future. A few days later he was dead. He had turned yellow and couldn’t speak at the end and yet I’m lying here now after taking an overdose a few hours ago. Yes you can die.

Comment by billyboom
2010-04-22 14:21:28

OMG WILL I DIE PLEASE TELL ME I WONT DIE IVE HAD ABOUT 20 OVERDOSES THIS YEAR AND THEVE BEEN MIXED EXEPT ONE OF 11 PARACETIMOL WICH WAS NOT MUCH :/ IVE HAD REALLY BAD TUMMY PAINS AND I DNT KNOW WHO TO TALK TO IM ONLY 14 AND IVE SPOKE TO MY PHSICS TEACHER AND HE SED IT DAMAGES YOUR STOMACHE LINING !! ANY ONE NO ANY MORE INFO

Comment by Zendy
2010-06-02 21:34:26

billyboom you will have to wait and see! you could have caused problems with your liver.
i dont know why you would do such a thing your life isnt so bad!

 
 
 
Comment by Rick
2010-02-14 23:10:47

Dear All, my wife has taken 10 tablets of Paracetamol 500 mg (tablet name: Domcet, having salts: paracetamol 500mg, domperidone BP 10mg), i already taken her to Emergency and they have given her CHARCOL so that it absorbs everything inside.

Do anyone have the same experience or know something about it? Will this be ok for the future? please email me or guide me, I shall be highly grateful for the same.

 
Comment by Mark
2010-02-16 07:03:57

My wife took some tablets on Thursday NIght. I made her sick and thought that would be OK, I went to Manchester working on Friday and on Sunday morning recieved a txt off her to say I needed to come home quick. She is now in hospital, She took about 100 tablets. Im not sure what to do. I may lose the only girl i ever loved.

Comment by billyboom
2010-04-22 14:22:55

I Took 11 and Refused To Go To Hospital, When I Took 8 I Had A Blood Sample But If An Adult Had Charcole Wll I Be OK :/

Comment by lizzie
2010-06-07 12:33:26

the biggest ive taken was 42 and ive taken regular doses of 16 im not dead. youll be fine if your worried go to the doctors, younger people’s bodies cope with things like this better for somereason thats what they told me. but now im gettin a bit ill well for a few weeks, go doctors

Comment by amanda
2010-07-25 23:57:09

well that is a really silly comment and not one that should be published. Panadol overdose needs to be treated within max 12 hours….you will receive a blood test from hospital who will know how much u have taken. Only upon result will you be given a drug called plavilax, through intravenous route. depends on the amount you have taken will depend if you get this..if you sort treatment and you did not get it then you fine. People dont realise that liver can be damaged straight away…doctors will keep and eye on your blood test results. If they are fine dont assume you will be fine forever as the effects of panadol overdose can creap up at a later stage. I work as a registered nurse in emergency department and I too have experienced first hand panadol overdose after a very personal horrific time I had. My panadol overdose was around 60 tablets….which is huge and I was not found till later and my treatment was over the 12 hours, …my blood test resolved and i was discharged…..however some months have past and I am happy with life and the direction I am taking, I am still very much working, but my liver results have started to change……..so think twice before you take panadol, it is not a drug that is likely to end your life straight away, and not worth the pain and heartache later in life. Talk Talk Talk ..to people, if you have no friends I know its hard, but seek councillor advice and talk to them please
regards amanda

 
 
 
Comment by more
2010-06-02 21:31:14

So is she alright?

 
 
Comment by Lisa
2010-02-21 16:55:52

I took 10 tablets of 500mg, but havent done anything about it. It’s been 4 days since and I’ve had no symptoms of any kind.

Comment by Lola
2010-03-10 02:06:42

LISA: I think that 10 is not going to kill you- maybe make you feel a bit unwell- but I am no doctor- all I really know is what I have read online- but maybe you should get yourself checked- you do not have to give all of your details- just your first name- and providing you are over 18- they cannot contact anyone- and if they don’t know your name or anything then how can they? better to be safe than sorry hey?
Take care.

 
 
Comment by Abby
2010-02-27 15:24:26

I took 10 paracetamols and it has been about a week since I had them, I haven’t had any symptoms or anything, does that mean I didn’t technically overdose

Comment by billyboom
2010-04-22 14:26:22

3 is classed as an overdose, i had 8 paretimol and wasnt effected but i got rushed to hospital and had to have a blood sample and stay in a few days, this year i had 3 extra strong paretimol and was effected more. i recently took 11 parectimol and ive had tummy pains ever since but what do i know im 14 hope that sort of helped :)

 
Comment by amum
2010-05-11 10:31:18

No. Technically you did. You will have done some damage to your liver which may be able to repair itself if it wasn’t too bad. You won’t neccessarily have symptoms but you will have done some damage even so.

 
Comment by lizzie
2010-06-07 12:34:38

yeh you over dosed but its doubtful you’ll be seriously ill :)

 
 
Comment by Carmen-Karima
2010-03-06 05:37:09

Ive taken 16 tablets of Ibuprofen and Anadin extra, yet i seem to be better then ever. How many more would i need to overdose? the only side affect is a pain in my belly, what can i do?

Comment by amum
2010-05-11 10:29:33

Get medical help. Ibuprofen and Aspirin (in Anadin) can cause internal bleeding – a long slow and painful death.

Comment by amanda
2010-07-25 23:59:54

very serious drug to take …aspirin can cause internal bleeding, bleed of the brain etc……with brufen, brufen alone has to be taken with food as it affects the lining of your stomach,,,,,,,,that with aspirin is not a good combination……amanda

 
 
Comment by Sadness
2010-06-02 21:10:16

Thats a bad thing you did! you used Ibuprofen :( i hear that causes stinking which is linked to Diarrhea.

im sticking with paracetamol becuse thats my friend :) not yours!

 
 
Comment by Carmen-Karima
2010-03-06 05:38:20

how else can i over doseeeee?!

Comment by Lola
2010-03-10 02:08:57

Not funny Carmen- and you know things must be pretty rubbish for you but lovely if you really meant it you would just have taken lots of anything- go talk to someone- or have a good cry- eat lots of food- give someone a cuddle- just be brave.

Comment by WUT
2010-06-02 21:08:26

Lola shut the fuck up you dont know what us people have to go though we are all DEPRESSED!

and thats made us choose to do bad things… becuse we didnt care what anyone thought and we felt lonley…. and some us us made bad decisions in life so if any of us overdose why should you care?
some of us only just do it again if it fails anyway. well the ones like us who dont have anything to live for.some people have things to live for, while others dont.

i feel like i have been useless all my life. depressed not wanting to do anything.

Comment by lizzie
2010-06-07 12:39:57

you have just made me feel very ashamed of being depressed.
that was such a wierd way of going about stating a point. you should be glad someone is making the effort to help someone tht is ill, my advice dont over dose, its hurts alot if you take loads and the lasting affects are differcult to deal with
you should go doctors if you feel bad they can organise help
i feel i have nothing to live for but the kindness tht person shows is a good thing not something to question
depressed people are thought of in a bad way, they way you just showed, we shouldnt be seen as selfish and unwantin to get better
good luck :) <3

 
Comment by faye
2010-07-06 16:32:11

Your Right There WUT I Feel Just Like Tht I Dont Want To Be Here AnyMore I Have No One I Can Go Too

So Thts Why I Think Your Dam Ritee!! x

 
Comment by Kelso
2010-07-13 05:53:17

You’d are all pathetic!!! If you want 2 kill your selfs do it properly and stop being attention seekers!

 
Comment by Damo
2010-07-18 05:47:09

Yeah I feel depressed most of my life. Everyone always saying “you can achieve anything” and all that crap, when nothing ever happens. Hope is gone, and I am trapped by a train-wreck past, that is not even all my fault. To be judged by the people who get everything, and don’t experience any significant pain I find is laughable. There are no true people left anymore, sometimes I think. All out to try and help, with that secret intention of controlling, or overpowering one.

I have attempted paracetamol overdose twice. The first time was 36×665 osteoparacetamol slow release tablets. I was in hospital for a week. My alts hit a high of approx 9900 and ast est 6800. I truly wanted to die, and die slowly – I just wanted to fucking feel something in this stupid no-hope fucked-up world. Even if the feeling was extreme nautia, and belly pain. It was something afterall.

The next attempt was only 10×665 tablets. (They only gave me the charcoal this time, not the pavalax, or whatever they put me on the first time for 7days.)

I did try the second time even after the specialist (the first time) mentioned there was a possibility I may require a liver transplant.

Now I take anti-depressants ( a tablet that makes me feel that which I don’t feel), I still fail to see the point. If life is so bad, that I need a stupid fucking tablet to make it “appear” that I am okay, then I would prefer to perish.

The only way I have come to justify this miserable shit-heap of an existence is……

Picture this…. (or not) … That there are no material possessions of value to you…..(just bear with me)…. There are no relationships that are important to you…. That there is no goal that is important to you …. That there is no objects at all…. There is no earth, no planets, no stars, no objects …. That you have no body… No legs, arms, abdomen, neck. You can not smell, touch, taste feel, hear. You also have no eyes…. as there is nothing to be seen. The only thing that exists is your consciousness, or awareness of the fact that you exist. Nothing else.

I believe that it is probable that mankind has evolved to being the most intelligent species that we ourselves know of because…. we are naturally destructive. We destroy nature, ourselves, we war with each other… etc. but perhaps that is the very reason… why we have become who we are.

No matter how hard life gets… we all are alone… we don’t like to admit it… I believe that is why religion was created… no one probably really wants to be alone (or not exist) … Despite our apparent overall tendency towards self destruction, the positive side to this is that we are good survivors. We have most probably killed more other species than any other. We are powerful beings. I must permit my awareness to exist I have convinced myself, as loneliness is inevitable anyways. I just no longer fear life, nor death as both are truly experienced alone.

Comment by /Jess
2010-07-29 15:15:28

i feel the same way Damo

 
 
Comment by /Jess
2010-07-29 15:12:23

my names jess and im 13 i know theres people that are far worse off then me in life but i just wanna be put into a deep sleep death isnt really the path i wanna go down ive never taken an overdose …

 
 
 
 
Comment by bob
2010-03-29 15:51:19

i have recently had a really tough time in life and started to think that i really didnt want to live. i get scared of myself when i randomly have urges to jump infront of cars or something although i know its not going to solve anything.
what should i do??

Comment by amum
2010-05-11 10:28:12

See your doctor and talk to him/her about it before it’s too late. Get help.

 
 
Comment by wendi
2010-04-11 15:31:34

i went n the contreceptive pill which gave e severe depression then everyhing in my life seemed to crumble around me so i decided to end my life however i stoped myself but i still consumed 10 parecetmols at once, in the morning when i woke up i was vomiting all day and was very disorientated but nothing more after that, then the other day i consumed another 8 parectemols at once and my breathing went all weird and i got chest pains. since then i have completly lost my appetite and have started loosing weight although i was quite tiny in teh first place. i also have really bad headaches and stomach pains what does this mean?

 
Comment by ally clare
2010-04-14 15:43:19

Anyone that’s thinking of taking an overdose… please, please don’t. I did it last year and I feel so insanely guilty about the massive scare I put the people I loved through. I didn’t really think about it at the time, was kind of a spur of the moment thing resulting from a long self-inflicted bout of depression. I know it’s hard not to be selfish when you’re depressed but really… do you want to make the people around you hurt? Chances are, no. Anyway from a personal perspective point of view – I took 80 tablets in total, 64 were paracetomol and 16 were aspirin. I was in hospital for about four days, felt the worst I’d ever felt, threw up disgustingly violently every time I tried to move, was on a drip, alienated my friends and family and caused massive tension. I don’t know how many can kill you and I don’t want to ever find out. Horrible to read the stories of people who nearly lost someone they loved, and it only adds to my feelings of guilt. Not too sure why i’m writing this but i’m just so so sorry that i put people through things becuase I was being horrible and selfish and I’d do anything never to have done it. Pleeeeeeas everyone be safe.

Comment by lovley
2010-06-02 21:01:34

So 80 cant kill you?

thank you ally clare your a life saver :)
i guess i will have to buy up to 120 boxes instead * Joking
geez cant you take a joke? hehe…..

Comment by jhon
2010-07-08 05:01:10

no coz that was not funny

 
 
 
Comment by Kitty_Kat
2010-04-15 11:07:26

I have survived a paracetemol overdose, when i was 13 i took 40 paracetemol and was in hospital about 10 weeks, i had severe kindey and liver failure, my organs were shutting down. I went through a really hard time and that was my way out, it was a cry for help!! I saw what it had done to my family, my OWN doing. I hated the fact i caused them soo much pain, but when you are in that state of mind you dont realise about anyone but yourself. It has been nearly 6 years since my overdose and all my organs are fine and healthy. I look at life totally different now, and think people in heaven must love me as i should of died. I am proud to say i am a survivor of an overdose. I wouldnt wish it upon anyone. Hope all is well xxxx

 
Comment by M
2010-04-21 00:16:45

Hey, I took 14 paracetamol tablets each 300mg, within 10 minutes, it has been two weeks and a bit more now and no symptons except for the initial dizziness and disorientation in the beginning after ingestion. I take it I have not overdose, and that I will be fine? I weigh 45kg, 17 year old female.
Thank you, your help will be much appreciated.

Comment by amum
2010-05-11 10:26:54

Yes you have overdosed. The Paracetamol will have damaged your liver even if you don’t have any symptoms at the moment. See your doctor now and get help for the underlying reasons why you took the overdose. If you ever take another one your liver will probably not be able to take it and you could die.

 
 
Comment by billyboom
2010-04-22 14:29:01

Ive took more than 20 overdoses this year some where mixesd and some wernt but ive had tumy pains since :/ any one help ?? x

Comment by amum
2010-05-11 10:23:50

Visit your doctor. Tell him/her what you have done. You need to get help for the underlying reasons you are taking the overdoses before it’s too late. The cumulative effect of the overdoses is slowly destroying your internal organs and one of these days it will be the final time and you WILL die. Get help now!

 
 
Comment by james270180uk
2010-04-23 02:23:33

I took an overdose in january of 48 500mg paracetamol as a suicide attempt and was rushed into hospital and i refused treatment i felt fine, i then took another attempt in february of 64 co-codamol 200mg and 120 500mg paracetamol and went into cardiac arrest but 3 hours later i discharged myself from hospital, in march i did the same but nothing happened apart from a small amount of blood in my urine and vomiting. now in april i took an overdose of 28 nitrazapam 5mg and 28 mitrazapime 30mg and again was taken into hospital and was discharged within 4 hours as my blood came back clean…… today i went to the doctors and was told my liver has only 25% functionality i may need a transplant

Comment by marina the fish fannie
2010-06-02 20:57:41

OW RLLY!

U MUS RLLY WAN 2 DIE!

 
 
Comment by annon
2010-05-13 06:24:10

i’ve been taking 20 panadol a day for about 2 years…obviously i worked up to it with starting with just five at a time….now i take ten in the morning and ten around lunch time…at first i had stommache pains but i don’t have them anymore….i’m a bit worried at teh moment because i took my usual 20 but now i’ve taken another 20 in the same day but over a period of 13 hours….hope i don’t die because i’m not doing it to suicide but i have a feeling i won’t feel to good in the morning

 
Comment by sammie
2010-05-19 13:13:26

ive just taken 6 paracentamols in 2 and a half hours , and errm will that do anything is it a overdose ?

 
Comment by annie
2010-05-20 11:37:17

hi. im not sure what to think. im going through what i think is a tough time. im a good person. have a great future ahead but i took 4 500mg paracetamol about 1 week ago, went to bed and was okay i guess as i slept most of the time (during night) but just now about 15 mins ago i consumed 8 500mg paracetomols. it was in the spur of the moment. not too sure what to do. its late in the evening now so if anything i will contact my doctors tomorrow. im 23, a female and weigh about 9stones. how does the equation thing work out. shall i try being sick? all ur help is and will be greatly appreciated. im getting a slight stich in my lower belly.

thank you.

 
Comment by anon
2010-05-25 09:41:28

my niece had an overdose tonight, she’s 14, weighs about 60 – 65kgs and took between 15 – 18 paracetamol, within a few hours of taking them, she showed symptoms of confusion, incoherant, drowsy and irratable, she is since in hospital overnight with treatment of charcoal and ECG and regular vital checks and a counselling referral, with the knowledge from the professionals (DOCTORS) that liver failure can occur after 3 days of overdose, i am surprised by how many ppl are on here asking complete strangers what “they” should do about their health, instead of the men and women who’ve dedicated yrs of study AND training, who could advise AND treat you in these circumstances, if you don’t want to consult your doctor, ask a pharmasist/chemist, who have also been trained or a nurse. i personally would advise seeking medical attention as soon as possible and visit your GP to arrange some kind of counselling, because obviously there is something you are not coping with well and are looking to overdose as a “quickfix” to make things “go away”, as i told my niece tonight, “if we lost you, we could never replace you”, think of those who love you before you take that plunge, seek help, there’s NO shame in admitting you need help!!

 
Comment by Shaiista x
2010-05-27 08:27:33

ii have just taken 23 paracetamol capsules (500g)
i feel nausic but i do</strike dont want to tell my family members that ii havee taken an overdose,
heelp? :O

Comment by Ponka
2010-06-02 20:53:44

well you proberly might get liver failure, hurry and see a doctor! before its to late you could be saved if you get the antidote now.

 
 
Comment by NASA
2010-05-30 08:58:25

I had a friend who OD’d on paracetamol tablets. She never made it. A massive dose with an improper tolerance test IS fatal if mixed with other barbs like blues or downers. If you or someone you know has taken a great quantity of these pills and is in and out of consciousness get to a medic IMMEDIATELY. Dying from liver damage is extremely unpleasant. Suicide is no way for you to die. Stay safe.

N.A.S.A

Comment by Zuzu
2010-06-02 20:55:41

and how is it unpleasant? is it a burning feeling? loads of screaming in pain?
and what happens when the person who has overdosed finally dies?
do they just close their eyes and go to sleep? well?

Comment by popm
2010-06-04 16:47:58

I dont think she knows which means she was lying

 
 
 
Comment by Sadness
2010-06-02 20:52:19

Oh Paracetamol your my only friend :) * hugs Paracetamol aww your so warm and burning, too many of you proberly would burn my insides

you might cause slow painful deaths but at least you dont cause stinking which is worst when it is linked to diarrhea.

ibuprofen has nothing on you paracetamol. oh paracetamol your the queen of queens! or kings w/e you are.

Comment by Zuzu
2010-06-02 20:56:06

ok…..

 
 
Comment by catrina
2010-06-03 06:47:49

can u plz help me i am 10 years old and i just took 8 capluts

Comment by muron
2010-06-03 10:02:28

Well Catrina i think you should go to the hospital, even 8 is enough for a OD
you will most likley vomit up most of it. your very lucky you didnt take more than 8

Comment by catrina
2010-06-03 23:17:25

thanks muron

 
 
 
Comment by Callie
2010-06-07 03:13:17

My sister is in the hospital right now on life support because she overdosed on paracetamol. She told me this morning that she had taken around 50 tabs in the last few days and asked me for advise on what to do. (she has also just started on antidepressents, which im guessing hasn’t started working yet).I imediently rushed her to the nearest hospital and has gotten worse and worse so quickly ever since and now here she is.
Anyway my point is my sister is now dying from having taken paracetamol over a period of time, not just all at once. She is 20 years old.

Comment by sothisiswhatwillhappentome
2010-06-07 15:31:16

So that is the outcome of only 50?

i guess that exsplains deaths from low dose paracetamol poisoning …
imagine taking 120 with asprin……… damn…. why oh why….

well heres the stages if anyone cares to read upon them….. of parecetemol poisoning.

Stage 1 (0.5-24 h postingestion)
- The first stage lasts for 24 hours.
- Patients have anorexia, nausea, vomiting, malaise, and diaphoresis. These clinical signs are nonspecific.

Stage 2 (24-72 h postingestion)
- The second stage begins 24 hours after ingestion and lasts for another 48 hours.
- Stage 1 symptoms become less evident than before and/or resolve.
- Patients present with pain and tenderness in the right upper quadrant. Liver enlargement (hepatomegaly) can be present. Some patients may report decreased urinary output (oliguria).
- Acute pancreatitis (eg, abdominal pain, elevated lipase, p-amylase) has been reported in patients who concurrently drink alcohol.

Stage 3 (72-120 h postingestion)
- Stage 3 develops 3-5 days after ingestion.
- Symptoms seen in stage 1 (eg, anorexia, nausea, vomiting, malaise) reappear along with signs of hepatic failure with jaundice, hypoglycemia, bleeding (coagulopathies), encephalopathy, and/or sepsis. Renal failure and cardiomyopathy may also occur.
- Renal involvement from acute tubular necrosis is evident with abnormal renal function studies, proteinuria, hematuria and granular casts on urinalysis. Acute renal failure occurs in 25% of patients with significant hepatotoxicity and in > 50% of those with hepatic failure.
- Death is most common during stage 3, with multiorgan failure as the primary cause.

Stage 4 (5-14 d postingestion)
- Stage 4 occurs 5-14 days after ingestion. This stage can last as long as 21 days.
- Patients either have a complete recovery of liver function or they die.
- In patients who recover, the period to normalization may take several weeks. Hepatic histiologic recovery lags behind clinical recovery and can take as long as 3 months to resolve.
- Acetaminophen-induced hepatotoxicity does not cause chronic hepatic dysfunction.

well Callie i wish you and your sister the best of luck xxxxxx
hope she makes it though.

 
 
Comment by Patricia
2010-06-12 12:32:20

does anyone no if the drug snowblow can cause you to take an overdose as my brother has recently overdosed on paracetemol after admitting to takin snow blow the night before, any advice is welcome please

 
Comment by daisy
2010-06-13 08:10:48

my sister took an overdose last night, the paramedics turned up and she refused to go…
he also said, that its not the fact she could die because the chanced of that is slim when taking an overdose of paracetemol, its the long term affects. :/ she took 18 and this was bad, so please don’t do it. im sure what ever is making you want to do this, isnt worth your death and pain to your loved ones :) xxx

 
Comment by John Wilkinson
2010-06-19 13:02:03

I have been taking Co-codamol for abpiy 8 years, I have severe arthiritis and sometimes take upto 8 a night, I was rushed intyo hospital following an accident and receiving a head injury, they did blood tests and it has come back I have serious Liver damage, this was over 8 years, I am seeing the Doctor Monday morning…I hope I surviive

 
Comment by Unsure.
2010-06-19 18:43:44

I’ve just taken 14 tablets containing 500mg of paracetemol. I plan on taking 6 more.
I’m 14.
Will this have any affect on me?

 
Comment by Possibly.
2010-06-21 06:17:10

Im 13 and I’m always popping pills.
I recently took 38 Paracetamol and told nobody, 12 hours later im bringing yellow vomit up, i can hardly move, what should I do, Im scared i’ll get shouted at and everything, But the stomach pains are so bad.

 
Comment by worried mum
2010-06-22 04:14:26

My 15 year old daughter took 8 paracetamole while at school yesterday. She seemed to slur her words and was very quiet. Took her to the local GP and the said she would be fine but they wouldnt know if she has caused liver damage for a few days. Have told her to see a counciler to get to the reason she done what she did.
It left me feeling like a bad mother as i did not notice she was feeling low.
All her friends and sister was in tears at school and it left my self and my husband feeling that we need to walk on egg shells now in fear of upsetting her!

Comment by Person with an attitude
2010-06-26 18:48:02

Well Worried mother! You need to Get up off your backside and keep a eye on her meaning you and your husband!

walking on eggshells in fear becuse of her emotions? I think you need to Keep your medicine Cabinets locked and keep the pills where she Cant get ahold of them.

somethings made her upset and unless you sort the problem out she will always be suicidal. everyone knows when they take more than one pill they are overdosing and hoping to kill themselfs. there is no such thing as a accidental OD, unless your drunk or drugged up to the max.

Im not sure how you and your husband brought up your daughter but she obviously has problems and if you dont sort them out its bound to get Worse!

also she needs to realise if she keeps that up she can end up dead or she can damage her liver and could eventually lead to death?

make her realise that she has alot to live for and also teach her that overdosing on any pill is a painful slow death. like i said anyone who overdoses must know it causes trouble.

well she only took 8 so she should be alright but it can cause major problems becuse taking over 2 is most likley a overdose or 4 or something like that.

Comment by bigger attitude!!!
2010-07-28 12:46:13

well person with attitude i think you have some cheek to speak to a concerned parent like that and even have a bigger nerve to question there perenting and the childs up bringing!!!!!! people have diffrent problems and sometimes a parent can give a child all the love in the world but the child will still find a problem its called BEEN A TEENAGER!!!! and the more you persue a chld to tell you the further they will go to hurt you, the best think to do with a child is not lock everything away as this will add to the problem and make the child go to greater lenghts to show there problem they will see the lack of trust you have in them and do worse next time!! the best think to do is watch your child (but not to the obvious extent miss attitude is telling you you dont want her to act on the trust issue 2) and get your daughter help but make sure shes ready, and in time your child will open up to you, sometimes its easier for a tteenager to talk to a stranger than there parents but by all means do ask your daughter if she wants to talk to you first as she may well want to but from my experience who was a teenager just like your daughter this is the best way it worked for me!! im 23 now married with 2 children my husband is a soldier and my life is perfect, re assure your daughter hers will be to!!!

 
 
 
Comment by Sarah
2010-07-04 17:44:24

i want to take an overdose, because i am all depressed :( i feel like i dont want to live nemore, i cant be dealin with all this nemore :( but im scared :’( i just want to take it and go to sleep what will happen to me…?

i love my family &+ friends very much (L) :’( xx

Comment by moomoo
2010-07-10 23:40:56

@sarah Didnt you just read the comments people left?

its a horrific death! and not worth it! besides you dont just die you stay alive for weeks in hospital and die a slow painful death while family members are beside you.

and if you live you then have to live in pain. and liver pains are TERRIBLE!

 
 
Comment by Sarah
2010-07-04 17:47:01

i forgot to say im 16, 17 in september, i weigh 6 stone and my hight is 4 ft 10.

 
Comment by Becca
2010-07-10 10:15:44

I took an overdose of 20 paracetamols on Tuesday because I felt worthless and unwanted. I received the treatment needed because about 7 hours after taking them the thought of death scared me so I told my parents, who took me to hospital straight away. I wouldn’t recommend it, it is the worst pain ever. I felt dizzy, I couldn’t stop vomiting, I felt so confused, I couldn’t speak and was also suffering from jaundice. Even after four days I still feel dizzy sometimes. I really thought I was going to die and it is the scariest thing ever, seriously not worth it. I’m now pretty confused because I thought that I wanted to get out of hospital, but now that I am, I would rather be back. Not sure why, but I think it is because I hate the thought of having to confront people and I am scared of the judgement I’m sure I will receive. I might possibly still have been in hospital today if I had told them I was still feeling down but to be honest; at the time I felt fine. I now feel my life will never be the same and I’m scared of what the long term affects will be.

Basically, if you are thinking of overdosing, try to find the strength not to and talk to someone. I wish I had just told someone because I wouldn’t be feeling the worst I’ve ever felt; and I’m only 19.

Comment by /Jess
2010-07-29 15:22:18

i wanna do that but im so scared of death i just wanna sleep forever and wake up wen everyone has forgiven me

 
 
Comment by phil simmonds
2010-07-26 15:55:20

2yrs ago i took 32 paracetamol and drank half a bottle of whisky, i read the last chapter of my book,closed my eyes and expected never to wake again.when i did wake i felt cheated but my mind was a little clearer and so i went to the hospital who offered me counciling, which is not for me. my question is that since that overdose i have gone completely off drinking water. from drinking 2 to 3 litres a day i cannot drink more than a sip full. any ideas as why

 
Comment by Julia Brooks
2010-07-28 07:55:09

I took 12 500mg paracetamol last friday, I weigh 73 kgs. I vomited twice half hour after taking the tablets. Is it likely to cause me problems now? I feel/have felt fine since vomiting.

 
Name (required)
E-mail (required - never shown publicly)
Your Comment (smaller size | larger size)
You may use <a href="" title=""> <abbr title=""> <acronym title=""> <b> <blockquote cite=""> <cite> <code> <del datetime=""> <em> <i> <q cite=""> <strike> <strong> in your comment.




© 2006 - 2007 Healthoma.com. You can link to the articles of this website from your websites but are not allowed to post the whole articles on your websites. Violators will be prosecuted.